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Two-photon absorption of polyfluorene aggregates stabilized by insulin amyloid fibrils

Hanczyc, Piotr and Justyniarski, Adrian and Gedefaw, Desta and Andersson, Mats R. and Samoc, Marek and Müller, Christian (2015) Two-photon absorption of polyfluorene aggregates stabilized by insulin amyloid fibrils. RSC Advances: an international journal to further the chemical sciences, 5 . pp. 49363-49368. ISSN 2046-2069

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We report on the photophysical and optical properties of a polyfluorene derivative (PFO) and its binding to the amyloid-forming protein insulin. The complexation is based on weak supramolecular interactions between amyloid fibrils and PFO in dissolved and aggregated form. In particular, complexes of polyfluorene aggregates display sizeable two-photon absorption when stabilized by insulin fibril nanotemplates. We propose that two-photon absorption enhancement mechanism is related to the combination of through-bond and through-space interactions of PFO. The findings reported here suggest that polyfluorene aggregates offer good nonlinear absorption properties and can be used as molecular markers for amyloid fibril recognition.

Item Type: Journal Article
Subjects: Q Science > Q Science (General)
Q Science > QD Chemistry
Divisions: Faculty of Science, Technology and Environment (FSTE) > School of Biological and Chemical Sciences
Depositing User: Generic Email
Date Deposited: 29 Aug 2018 02:15
Last Modified: 03 Oct 2022 01:02

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