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Stereoselective synthesis of N-alkylaziridines from N-chloroamines

Bew, Sean P and Hughes, D. L. and Palmer, Nicholas J. and Savic, Vladimir and Soapi, Katy M. and Wilson , Martin A. (2006) Stereoselective synthesis of N-alkylaziridines from N-chloroamines. Chemical Communications, 41 . pp. 4338-4340. ISSN 1359-7345

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We report the first racemic and stereoselective synthesis of cis- and trans-N-alkylaziridines via N-chloroamines; using this methodology an N-3,4,5-trimethoxybenzylaziridine was synthesised and efficiently cleaved, affording the corresponding NH aziridine in high yield.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Science, Technology and Environment (FSTE) > School of Biological and Chemical Sciences
Depositing User: Repo Editor
Date Deposited: 24 Nov 2016 02:36
Last Modified: 24 Nov 2016 02:36

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