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Expedient synthesis of substituted (S) - N - (α-methylbenzyl) aziridines

Bew, S.P. and Hughes, D.L. and Savic, V. and Soapi, Katy M. and Wilson, M.A. (2006) Expedient synthesis of substituted (S) - N - (α-methylbenzyl) aziridines. Chemical Communications, 33 . pp. 3513-3515. ISSN 1359-7345

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We report for the first time that after O-acylation the conjugate addition products of (S)-N-(α-methylbenzyl)hydroxylamine undergo an efficient diastereoselective 3-exo-tet ring-closure reaction affording 2- and 2,3-disubstituted-N-alkylaziridines in good to excellent yields.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Science, Technology and Environment (FSTE) > School of Biological and Chemical Sciences
Depositing User: Repo Editor
Date Deposited: 15 Dec 2016 03:04
Last Modified: 15 Dec 2016 03:04

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