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Identification and characterization of the actinomycin G gene cluster in Streptomyces iakyrus

Wang, Xiaoling and Tabudravu, Jioji N. and Rateb, Mostafa E. and Annand, Krystal J. and Qin, Zhiwei and Jaspars, Marcel and Deng, Zixin and Yu, Yi and Deng, Hai (2013) Identification and characterization of the actinomycin G gene cluster in Streptomyces iakyrus. Molecular BioSystems, 9 (6). pp. 1286-1289. ISSN 1742-206X

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Abstract

The gene cluster directing actinomycin G biosynthesis in Streptomyces iakyrus has been identified and sequenced. It contains one actinomycin synthetase I (ACMS I) gene and two copies of ACMS II and III genes. Genetic analysis demonstrates a unique partnership between the putative hydroxylation and chlorination activities as both acmG8 and acmG9 genes need to be transcribed for the biosynthesis of actinomycin G2–3, respectively.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Science, Technology and Environment (FSTE) > School of Biological and Chemical Sciences
Depositing User: Fulori Nainoca
Date Deposited: 18 May 2017 13:34
Last Modified: 04 Jul 2017 11:06
URI: http://repository.usp.ac.fj/id/eprint/9901
UNSPECIFIED

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