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Clionasterol, a Triterpenoid from the Kenyan Marine Green Macroalga Halimeda macroloba

Dzeha, Thomas and Jaspars, Marcel and Tabudravu, Jioji N. (2003) Clionasterol, a Triterpenoid from the Kenyan Marine Green Macroalga Halimeda macroloba. Western Indian Ocean Journal of Marine Science, 2 (2). pp. 157-161. ISSN 0856-860X

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    Abstract

    The triterpenoid clionasterol (1), a 29 carbon structure compound was isolated from the less polar extract (20% EtOAc in hexanes) of the green alga Halimeda macroloba collected at Shimoni near Mombasa, Kenya. The structure and relative stereochemistry of this compound was elucidated by spectroscopic data, mainly NMR and mass spectrometry. This metabolite was inactive against DLD-1 cells on the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. Further experiments on mosquito larvae and brine shrimp lethality confirmed this result.

    Item Type: Journal Article
    Uncontrolled Keywords: clionasterol, macroalga, Halimeda macroloba, spectroscopy, bioprospecting, Kenya
    Subjects: Q Science > QD Chemistry
    Divisions: Faculty of Science, Technology and Environment (FSTE) > School of Biological and Chemical Sciences
    Depositing User: Repo Editor
    Date Deposited: 06 Jun 2017 15:04
    Last Modified: 06 Jun 2017 15:04
    URI: http://repository.usp.ac.fj/id/eprint/9928
    UNSPECIFIED

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