Stout, E.P. and Hasemeyer, A.P. and Lane, A.L. and Davenport, T.M. and Engel, S. and Hay, M.E. and Fairchild, C.R. and Prudhomme, J. and Le Roch, K. and Aalbersberg, William G.L. and Kubanek, J. (2009) Antibacterial Neurymenolides from the Fijian red alga Neurymenia fraxinifolia. Organic Letters, 11 (1). pp. 225-228. ISSN 1523-7060
Full text not available from this repository.Abstract
Two novel α-pyrone macrolides, neurymenolides A (1) and B (2), were isolated from the Fijian red alga Neurymenia fraxinifolia and characterized using a combination of NMR and mass spectral analyses. These molecules represent only the second example of α-pyrone macrolides, with 1 existing as interchanging atropisomers due to restricted rotation about the α-pyrone ring system. Neurymenolide A (1) displayed moderately potent activities against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistantEnterococcus faecium (VREF).
| Item Type: | Journal Article |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science, Technology and Environment (FSTE) > Institute of Applied Science |
| Depositing User: | Ms Neha Harakh |
| Date Deposited: | 24 May 2009 02:12 |
| Last Modified: | 18 Jul 2012 07:08 |
| URI: | http://repository.usp.ac.fj/id/eprint/1506 |
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