Srinivasa, Chandrashekar and Santhosh, Kumar and Pradeep, Sushma and Prasad, Shashanka and Veerapur, Ravindra and Ansari, Mohammad and Alomary, Mohammad and Alghamdi, Saad and Almehmadi, Mazen and GC, Kavitha and Daphedar, Azharuddin and Kakkalameli, Siddappa and Shivamallu, Chandan and Kollur, Shiva P. (2022) Eco - friendly synthesis of MnO2 Nanorods using Gmelina arborea fruit extract and its anticancer potency against MCF-7 breast cancer cell line. International Journal of Nanomedicine, 17 . pp. 901-907. ISSN 1176-9114
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Abstract
The formation of MnO2 NPs was confirmed through powder X-ray diffractometer (XRD), scanning electron microscopy (SEM),
transmission electron microscopy (TEM) and high-resolution transmission electron microscopy (HR-TEM). The crystalline nature of asprepared MnO2 NPs was evident from XRD pattern. The morphology of the material was studied using SEM analysis, which suggested a rod-like nature with an average diameter of 50 nm. Further, the TEM and HR-TEM images confirmed the rod shape of the as-prepared MnO2 NPs with an interplanar distance of 0.271 nm. In addition, the concentric rings from selected area electron diffraction (SAED) analysis show the crystalline nature of the as-prepared material, which further supports the obtained XRD pattern. The anticancer efficacy of MnO2 NPs was evaluated against MCF-7 breast cancer cell line, which showed up to 96% inhibition of the cells at 400 μg/mL concentration.
| Item Type: | Journal Article |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Divisions: | School of Agriculture, Geography, Environment, Ocean and Natural Sciences (SAGEONS) |
| Depositing User: | Shiva Prasad Kollur |
| Date Deposited: | 03 Mar 2022 23:30 |
| Last Modified: | 22 Oct 2024 10:32 |
| URI: | http://repository.usp.ac.fj/id/eprint/13273 |
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