Lane, A.L. and Stout, E.P. and Lin, A.S. and Prudhomme, J. and Roch, K.L. and Fairchild, C.R. and Franzblau, S.G. and Hay, M.E. and Aalbersberg, William G.L. and Kubanek, J. (2009) Antimalarial bromophycolides J-Q from the Fijian red alga Callophycus serratus. The Journal of Organic Chemistry, 74 (7). pp. 2736-2742. ISSN 0022-3263
Full text not available from this repository.Abstract
Bromophycolides J−Q (1−8) were isolated from extracts of the Fijian red alga Callophycus serratus and identified with 1D and 2D NMR spectroscopy and mass spectral analyses. These diterpene−benzoate macrolides represent two novel carbon skeletons and add to the 10 previously reported bromophycolides (9−18) from this alga. Among these 18 bromophycolides, several exhibited activities in the low micromolar range against the human malaria parasite Plasmodium falciparum.
| Item Type: | Journal Article |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science, Technology and Environment (FSTE) > Institute of Applied Science |
| Depositing User: | Ms Neha Harakh |
| Date Deposited: | 24 May 2009 02:12 |
| Last Modified: | 12 Jul 2012 08:52 |
| URI: | https://repository.usp.ac.fj/id/eprint/1475 |
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