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Papuamides E and F, cytotoxic depsipeptides from the marine sponge

Prasad, Pritesh and Aalbersberg, William G.L. and Feussner, Klaus D. and Wagoner, R.M.V. (2011) Papuamides E and F, cytotoxic depsipeptides from the marine sponge. Melophlus sp. Tetrahedron, 67 (44). pp. 8529-8531. ISSN 0040-4020

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Abstract

Two known papuamides C (1) and D (2) together with two new depsipeptides, papuamides E (3) and F (4), were isolated from an undescribed sponge of the genus Melophlus collected in the Solomon Islands. The planar structures of the compounds were elucidated on the basis of spectroscopic studies. Papuamides C–F (1–4) showed cytotoxicity against brine shrimp with LD50 values between 92 and 106 μg/mL.

Item Type: Journal Article
Subjects: Q Science > Q Science (General)
Divisions: Faculty of Science, Technology and Environment (FSTE) > Institute of Applied Science
Depositing User: Ms Shalni Sanjana
Date Deposited: 25 Jun 2011 02:46
Last Modified: 25 Jun 2012 02:46
URI: https://repository.usp.ac.fj/id/eprint/4805

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