Callophycoic acids and callophycols from the Fijian red alga Callophycus serratus

Lane, A.L. and Stout, E.P. and Hay, M.E. and Prusak, A.C. and Hardcastle, K. and Fairchild, C.R. and Franzblau, S.G. and Roch, K.L. and Prudhomme, J. and Aalbersberg, William G.L. and Kubanek, J. (2007) Callophycoic acids and callophycols from the Fijian red alga Callophycus serratus. The Journal of Organic Chemistry, 72 (19). pp. 7343-7351. ISSN 0022-3263

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Abstract

Callophycoic acids A−H (1−8) and callophycols A and B (9 and 10) were isolated from extracts of the Fijian red alga Callophycus serratus, and identified by NMR, X-ray, and mass spectral analyses. These natural products represent four novel carbon skeletons, providing the first examples of diterpene−benzoic acids and diterpene−phenols in macroalgae. Compounds 1−10 exhibited antibacterial, antimalarial, and anticancer activity, although they are less bioactive than diterpene-benzoate macrolides previously isolated from this red alga.

Item Type:	Journal Article
Subjects:	Q Science > QD Chemistry
Divisions:	Faculty of Science, Technology and Environment (FSTE) > Institute of Applied Science
Depositing User:	Ms Mereoni Camailakeba
Date Deposited:	24 May 2007 03:18
Last Modified:	29 Aug 2012 05:05
URI:	https://repository.usp.ac.fj/id/eprint/750

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