Soapi, Katy M. and Hutton, C.A. (2006) Preparation of β - nitroalanine using the Easton three - component coupling method. Amino Acids, 31 (3). pp. 337-339. ISSN 0939-4451
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Official URL: http://link.springer.com/article/10.1007/s00726-00...
Abstract
A simple one-step preparation of β-nitroalanine has been developed using the Easton three-component coupling method. To date one limitation of this method has been that use of nitromethane as the nitroalkane component does not yield β-nitroalanine. We report that use of the dipotassium salt of nitroacetic acid in the Easton three-component coupling gives β-nitroalanine in high yield, presumably via facile decarboxylation of a β-nitroaspartate intermediate.
| Item Type: | Journal Article |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science, Technology and Environment (FSTE) > School of Biological and Chemical Sciences |
| Depositing User: | Repo Editor |
| Date Deposited: | 15 Dec 2016 02:43 |
| Last Modified: | 15 Dec 2016 02:43 |
| URI: | https://repository.usp.ac.fj/id/eprint/9477 |
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