Tabudravu, Jioji N. and Morris, Linda A. and Milne, Bruce F. and Jaspars, Marcel (2005) Conformational studies of free and Li+ complexed jasplakinolide, a cyclic depsipeptide from the Fijian marine sponge Jaspis splendens. Organic & Biomolecular Chemistry, 3 (5). pp. 745-749. ISSN 1477-0520
Full text not available from this repository. (Request a copy)Abstract
The complexation of Li+ to jasplakinolide, a marine sponge derived cyclic depsipeptide showed preferential binding to two out of four carbonyl oxygens (C-10, C-14) and the electrons of the aromatic system of the β-tyrosine amino acid residue. This is in contrast to previous results obtained by others who proposed complexation to three out of four available carbonyl oxygens (C-1, C-10, C-14). The structure of the complex in CD3CN was determined by NOE restrained molecular dynamic calculations. Structures of the uncomplexed jasplakinolide were calculated in CDCl3 and CD3CN for comparison.
| Item Type: | Journal Article |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science, Technology and Environment (FSTE) > School of Biological and Chemical Sciences |
| Depositing User: | Repo Editor |
| Date Deposited: | 06 Jun 2017 03:09 |
| Last Modified: | 03 Jul 2017 23:34 |
| URI: | https://repository.usp.ac.fj/id/eprint/9927 |
Actions (login required)
 |
View Item |