Dzeha, Thomas and Jaspars, Marcel and Tabudravu, Jioji N. (2003) Clionasterol, a Triterpenoid from the Kenyan Marine Green Macroalga Halimeda macroloba. Western Indian Ocean Journal of Marine Science, 2 (2). pp. 157-161. ISSN 0856-860X
Preview |
PDF
- Published Version
Download (137kB) | Preview |
Abstract
The triterpenoid clionasterol (1), a 29 carbon structure compound was isolated from the less polar extract (20% EtOAc in hexanes) of the green alga Halimeda macroloba collected at Shimoni near Mombasa, Kenya. The structure and relative stereochemistry of this compound was elucidated by spectroscopic data, mainly NMR and mass spectrometry. This metabolite was inactive against DLD-1 cells on the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. Further experiments on mosquito larvae and brine shrimp lethality confirmed this result.
| Item Type: | Journal Article |
|---|---|
| Uncontrolled Keywords: | clionasterol, macroalga, Halimeda macroloba, spectroscopy, bioprospecting, Kenya |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science, Technology and Environment (FSTE) > School of Biological and Chemical Sciences |
| Depositing User: | Repo Editor |
| Date Deposited: | 06 Jun 2017 03:04 |
| Last Modified: | 06 Jun 2017 03:04 |
| URI: | https://repository.usp.ac.fj/id/eprint/9928 |
Actions (login required)
 |
View Item |