Tabudravu, Jioji N. and Morris, Linda A. and den Bosch, J. Jantina Kettenes-van and Jaspars, Marcel (2002) Axinellin C, a proline-rich cyclic octapeptide isolated from the Fijian marine sponge Stylotella aurantium. Tetrahedron, 58 (39). 7863 - 7868. ISSN 0040-4020
Full text not available from this repository. (Request a copy)Abstract
The structure of a new cyclic octapeptide, axinellin C, (cyclo[Thr1-Val2-Pro3-Trp4-Pro5-Phe6-Pro7-Leu8]), with all-trans peptide bond geometry, was elucidated by a combination of 2D NMR methods and tandem mass spectrometry. The solution state conformation was determined by ROE restrained molecular dynamics calculations. The structural features were found to be similar to those of the crystal structure of the cyclic decapeptide, phakellistatin 8, despite differing peptide sequences.
| Item Type: | Journal Article |
|---|---|
| Additional Information: | Supports Open Access |
| Uncontrolled Keywords: | natural products; amino acids; peptides; Stylotella aurantium; sponge; nuclear magnetic resonance; mass spectrometry; restrained molecular dynamics; solution conformation |
| Subjects: | Q Science > QD Chemistry Q Science > QH Natural history > QH301 Biology |
| Divisions: | Faculty of Science, Technology and Environment (FSTE) > School of Biological and Chemical Sciences |
| Depositing User: | Repo Editor |
| Date Deposited: | 06 Jun 2017 02:57 |
| Last Modified: | 06 Jun 2017 02:57 |
| URI: | https://repository.usp.ac.fj/id/eprint/9930 |
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