Tabudravu, Jioji N. and Morris, Linda A. and Bosch, J.Jantina Kettenes-van den and Jaspars, Marcel (2001) Wainunuamide, a histidine-containing proline-rich cyclic heptapeptide isolated from the Fijian marine sponge Stylotella aurantium. Tetrahedron Letters, 42 (52). pp. 9273-9276. ISSN 0040-4039
Full text not available from this repository. (Request a copy)Abstract
The isolation and structure determination of an unusual cyclic heptapeptide, wainunuamide, from a Fijian marine sponge, Stylotella aurantium, is reported. The peptide contains three proline residues and a histidine residue, which is rare in cyclic peptides and has only previously been reported in a cyclic peptide isolated from the cyanobacterium Oscillatoria agardhii, suggesting a possible source of the peptide. Wainunuamide is found to have weak cytotoxic activity.
| Item Type: | Journal Article |
|---|---|
| Uncontrolled Keywords: | sponges; cyclic peptides; NMR; MS; cytotoxicity |
| Subjects: | Q Science > QD Chemistry Q Science > QH Natural history > QH301 Biology |
| Divisions: | Faculty of Science, Technology and Environment (FSTE) > School of Biological and Chemical Sciences |
| Depositing User: | Repo Editor |
| Date Deposited: | 06 Jun 2017 00:14 |
| Last Modified: | 03 Jul 2017 23:56 |
| URI: | https://repository.usp.ac.fj/id/eprint/9940 |
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